CBD and the liver The FDA warns that CBD can cause liver damage. In clinical studies with Epidiolex, high levels of liver enzymes were the main reason why treatment had to be stopped. This is because high levels of liver enzymes can be a sign of liver damage. However, initial findings suggest that the side effects are minimal and that only if you take a comparatively high dose of CBD oil could your liver be affected.
Critics called for a human study, such as that of Validcare, arguing that there are differences between how CBD works in mice and that in humans, and that most people would not ingest the level of CBD that the rodents received in the study. Ocean Spray's Lighthouse incubator launched a CBD sparkling water line called CarryOn, while Canopy Growth, from Constellation Brands, launched its own sparkling CBD drink, Quatreau. Few studies have been conducted on liver test abnormalities during treatment with lower doses of CBD or with commercially available over-the-counter CBD products. Truss CBD USA, a partnership between Molson Coors Beverage Company and Canadian cannabis grower Hexo, has also introduced a sparkling CBD drink called Veryvell in the US.
Despite its roots in the cannabis plant, it's legal to buy CBD oil in the UK and many other countries around the world, and many consumers say it's effective for relieving pain, fighting nausea and stress, and more than a third of consumers say it helps alleviate anxiety. Thinh Vo, director of quality and compliance at Koi CBD, a provider of laboratory-certified CBD products, says that CBD users need to remember that mice and people are very different.